Spyware message in background

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Hi guys, I logged onto my computer today, and my desktop has been replaced to a white background with a box saying:

"Warning!
Spyware detected on your computer!

Install an antivirus on your computer

Warning! Win32/Adware.Virtumonde
Detected on your computer

Warning! Win32/PrivacyRemover.M64
Detected on your computer"

I can't click anywhere on it, it's just part of the background, and I can't change my background or screensaver, (tried control panel and right clicking on desktop) tried virus scan, nothing, tried spyware scan, nothing.

I followed another threads advise, download SmitFraudFix v.2.353, and ran it (both safe mode and when it didn't work in normal mode), and have tried it so many times. But after I turn off my comp, and back on after, the message is back. I can get rid of it and return my desktop to its former glory running SmitFraudFix, but it changes back to the message upon reboot.

Can anyone PLEASE help?

(From what I've seen so far, alot of people have had this problem too)
 
Thanks, I downloaded that Malwarebytes thing and used that, turns out the main source of my problem was Video Egg Publisher...Well, it's fixed now, so thanks again *gives cookie of appreciation*
 
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