Virus programs not responding

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Hey, I have a few computers here that seem to be effected by the same virus/malware.

They are all not able to open programs in safe or normal mode.

Tried to run system restore but would not be able to proceed when it normally would start running the restore.

when conecting a usb device it comes up saying removable device (not the name of the device) and when trying to open it, it says insert media.

also am not able to install new programs in either safe mode or normal mode. and cannot open previously installed programs.



I ran several programs to try and find the bug externally including symantec corp. avg. and malwarebytes, none found anything that would cause these issues
 
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