Bryan Johnson, the millionaire biohacker who wants to live forever, diagnosed with incurable autoimmune disease

midian182

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Facepalm: Bryan Johnson, the tech millionaire famous for his many biohacking procedures as he attempts to live forever, has been diagnosed with an incurable autoimmune disease. The subject of the Netflix documentary Don't Die: The Man Who Wants to Live Forever has autoimmune gastritis (AIG), a condition which, in Johnson's words, has led to his stomach "eating itself."

Johnson revealed his diagnosis on Instagram. He wrote that 2-5% of people have autoimmune gastritis, though the number may be higher as it can be hard to spot in its early stages.

Not one to be deterred by an incurable autoimmune condition, Johnson says he will try to "solve" his illness and will share everything he learns.

The Braintree founder has tried many ways to reverse and even stop the aging process, the most famous being injecting himself with plasma from his teenage son.

He was also taking 54 supplements every day, though he discovered last year that one of them, an immunosuppressant called rapamycin originally used to prevent organ rejection, was actually aging him.

In his post, Johnson blames his diet of cereal, soda, and fast food as a kid, combined with the stress of later becoming a father of three and building a business, for his autoimmune conditions – he was also diagnosed with autoimmune hypothyroidism at age 21.

While lifestyle factors can increase the risk of developing some autoimmune conditions, their exact cause is unknown – genetics and environmental triggers are believed to play the biggest roles. And people who develop one often get others.

Johnson said one of the main indicators that he had AIG was his 11 years of low ferritin levels, which indicate low stored iron. Having a vegan diet meant Johnson took iron tablets, but they weren't raising his ferritin levels.

A colonoscopy, an upper endoscopy, and five biopsies of his stomach confirmed clear signs of early autoimmune gastritis.

AIG treatment involves managing the disease, but Johnson said in the "age of AI, multiomics, and custom-built DNA, proteins, and cells, no condition should be presumed incurable" just because nobody has tried to cure it with today's technology.

Johnson is said to spend around $2 million annually on his health regimen, which includes a plant-based diet, avoiding the sun, and daily exercise. He's also used shock treatments on his genitals in an apparent effort to gain the erections of an 18-year-old.

Johnson earned over $300 million when his mobile and web payment company Braintree was acquired by PayPal in 2013. He now sells his own (very expensive) supplement stacks and individualized health regimens under the Blueprint name.

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We are 5 million year old apes, based on 50million year old mammals. This guy fooling around with his diet or injecting his son's blood plasma will change a surface effect only. Being alive at all is chance in all our lives - cross the street 5 seconds too early or too late - possible death at age 9. Do everything in moderation and don't pretend you can programming the human body. Online fitness vlogerscdie left and right in their latec20s.. Bruce Lee the first fitness gurue fraud died in his 30s.
 
He discovered last year that one of them, an immunosuppressant called rapamycin originally used to prevent organ rejection, was actually aging him.
This isn't quite correct. Johnson noted a preprint study that found rapamycin to accelerate the pace of several epigenetic clocks.

That study itself is interesting, as it compares the effects of a large variety of anti-aging regimens:
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Maybe rich people with a normally functioning brain do actually exist. But I don't know any.
Do remember that there is quite a bit of selection bias here; rich people who are "eccentric" in various ways will make the news since their antics are amusing, while all the rich people doing more normal boring things (well, fancier more expensive versions of the normal things) will not make the news since well that is boring.
 
Can I say I find it really surprising that this guy is basically running these experiments on himself? I mean if you have enough money then funding studies and having stuff tested on other people first seems like a better option. Granted, he might not be in wealth bracket to afford full out studies like that; tech "millionaire" is pretty vague in exactly how much money he has. I am surprised that we don't see more older, wealthy billionaires tossing funds at anti-aging research. For someone like say Warren Buffet, who is 95 years old, what would he have to lose by tossing a few billion at that field?
 
So, he is simply insane.
No, I don't think he's insane. We know of many types of dysmorphia. Body dysmorphia, gender dysmorphia, and muscle dysmorphia are the most common ones.

This guy seems to have some form of general health dysmorphia where he is convinced he must change his health through ever more aggressive means. He's not the only one, there are plenty of health nuts who do insane things trying to be healthier. He just has a lot more money then most and can afford more extreme measures.

And since he already had a different autoimmune condition, it's possible this guy has felt unwell most of his life and that has shaped his mind.
 
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"No man can redeem the life of another or give to God a ransom for him—the ransom for a life is costly, no payment is ever enough—so that he should live on forever and not see decay."
-- Psalm 49:7-9
 
This guy seems to have some form of general health dysmorphia
You don't need to misuse terms to explain the ubiquitous desire of humans to live longer. Rapamycin dramatically extends the lifespan of mice and some other animals, and it's been deemed FDA-safe for human consumption for decades: what's so strange about him testing that upon himself? Early cancer researchers intentionally injected themselves with cancer cells and even sewed live tumors from other patients into their own body. Compared to that, this n-of-one study is hardly extreme.
 
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You just don’t hear about them because they aren’t doing click worthy things. Just quietly enjoying the good life.

Exactly, I know a few and they are doing exactly as you say, Nice houses, nice cars, going on holidays, track days etc... Not spending time on social media or self experimentation. I own a Nissan Skyline and our club has a number of wealthy people in, That's how I know them.

I also have an auto immune disease, Ulcerative colitis, The nuclear option is to remove parts of the bowel. I wonder if the stomach can be partly removed to mitigate his problem.
 
It is 100% guaranteed you will die one day, unavoidable!! The massive amounts of supplements you are taking is probably causing more harm than good. It is well established scientifically that supplements are passed through with little absorption. As Sheldon said; "You are paying for expensive urine."
 
We are 5 million year old apes, based on 50million year old mammals. This guy fooling around with his diet or injecting his son's blood plasma will change a surface effect only. Being alive at all is chance in all our lives - cross the street 5 seconds too early or too late - possible death at age 9. Do everything in moderation and don't pretend you can programming the human body. Online fitness vlogerscdie left and right in their latec20s.. Bruce Lee the first fitness gurue fraud died in his 30s.

Your premise ("will change a surface effect only") is silly. If that were the case, we'd all still be dying of smallpox, bubonic plague, and more. We have bioengineered humans such that a great many of the things that killed us in the past no longer do so (or affect only a tiny proportion of humanity).

He's actually doing humanity a service - he's basically doing experimental research directly on a human, and bypassing the lengthy processes involved in getting new medications to humans (animal trials first, etc etc).

And by the way, no, Bruce Lee was not 'the first fitness guru'.
 
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It is 100% guaranteed you will die one day, unavoidable!! The massive amounts of supplements you are taking is probably causing more harm than good. It is well established scientifically that supplements are passed through with little absorption. As Sheldon said; "You are paying for expensive urine."

'well established scientifically that supplements are passed through with little absorption'.

Please don't make up claims and cloak things as "scientifically proven". Your claim is absolute hogwash, no science backing it.

Feel free to provide reliable sourcing to prove your claim.

In other words... [[citation needed]]
 
He is insane, like most tech bros and paypal mafia billionaires. They are all extremely materialistic, probably all atheists or satanists, and are absolutely terrified of the idea of aging and death - since they don't want their comfortable and luxurious lives to end, and are sure it's just lights out after (and maybe it is, personally I don't care). In all eras through history there have always been people unhealthily obsessed with the fear of aging and dying, but these 21st century tech bros have been taking it to a whole new level.

Since most anti-aging therapies appear to be failing or not showing good enough results, I'm sure most of them will eventually resort to things like cryogenic preservation, or begin heavily investing in research and tech to attempt to upload their minds to computers.

But I digress. About the Bryan Johnson guy, I'm sure all these crazy therapies probably helped trigger his autoimmune disorder. If he keeps this up, he'll end up killing himself instead of living longer.

"He's also used shock treatments on his genitals in an apparent effort to gain the erections of an 18-year-old."

Wow, that's sooo early 20th century that it made me laugh. I'm sure people must have tried this during the peak of the shock therapy hysteria between the 1910s-1930s.

Next thing, he'll try to use radiation therapy on his genitals.
 
Exactly, I know a few and they are doing exactly as you say, Nice houses, nice cars, going on holidays, track days etc... Not spending time on social media or self experimentation. I own a Nissan Skyline and our club has a number of wealthy people in, That's how I know them.

I also have an auto immune disease, Ulcerative colitis, The nuclear option is to remove parts of the bowel. I wonder if the stomach can be partly removed to mitigate his problem.
I love that you mentioned track days because that is also how I have met many chill rich people. Just the motorcycle version.

Hope the AID stays manageable and may your lap times always get faster.
 
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