Sure, if you're having issues with using the keyboard and mouse, you'll get used to it.
WASD move, WASD is a common way of saying W, A, S, and D keys.
W: forward
A: left strafe
S: backwards
D: right strafe
Those are the movement keys. If you use your mouse, you can look around, and left clicking shoots the gun, and the right click depends on the game.
It should tell you other keys while playing, and if not, then open up the options and look around at the buttons.
Is there something in particular you'd like to know, mega-64?