I can vouch for Revo Pro. It's rather cheap at the moment, especially for a two year licence.
Been using it for years. Intuitive, and gives plenty of options.
Has a lot of other useful tools too.
As for the registry tuner. (Seperate program) Well, I am wary of them but run a safe scan from time to time.
It's main use is Windows 11 customization, such as bringing back the old right click menu (Win 10) and a lot of others.
In fact a two week trial will allow you to do all these optimizations for free. The program itself is very cheap for the pro, but I am wary to recommend ANY registry cleaner.