I was thinking on the similar lines as well Captain and have moved one of the fans as such. However, keeping in mind your experience I think I'll need to make few more openings to improve the airflow further.
The first thing I noticed on that board was heatsinks, and frankly 'said few colorful words' about Intel for not doing a good job in this area.
Yup luckily, I've always selected what components I want to buy, then went ahead and put them together, and since the days of 486DX-100 I never bought non-Intel boards for one reason only, they are simple (read over engineered as DBZ rightly said) no frills solution, also generally are very very stable and reliable platforms. Thanks you