The computer specs: Packard Bell iMedia 1408 P4 516 2.93GHz Stock Cooler Asus P5S800-VM 2GB DDR333 RAM (one stick is DDR333 the other is DDR400, the 333 stick was added recently, but the problem was occuring before that) BFG 7600GS 512MB 160GB IDE HDD IDE DVD-RW XP Home SP3 The problem: This is a family machine, its turned on first thing and turned off at night. If we turn it on in the morning, and go to use it in the late afternoon (after not being used for a few hours), if we click on a desktop shortcut to load a program, it won't load. The computer is responsive, it just won't load any programs. If we restart the machine, it works fine. As far as we can remember, this just happened all of a sudden a couple of months back, with no change we've done causing it. I've had a look, and I can't see any restore points for the 2 or 3 weeks when this problem started. Things we've done: Virus scan (with Virgin Media Security and Stinger), no viruses. Attempted System Restore, no points to go back to around the time this started happening. Any ideas? I can't think of much without reinstalling, which realistically isn't feasible at the moment.