Media in DVD Drive is not readable

I burn a fair amount of DVR disks with games, movies, and personal files. The drive works just fine. I can play DVDs and it reads other disk. However, I have one disk that just isn't reading at all. I ran the Windows Fix it says the media is not readable. When I insert the disk it is loading in the My Computer screen, and then makes a load funny sound and just doesn't read the disk. When it finishes, the drive ejects when you click on it and says to insert a disk. I looked at ISObuster and it also picks up nothing. I'm not 100% certain, but I'm pretty sure the disk was readable at one time. The disk doesn't appear to have any scratches, cracks, etc. Is there anything I can do to get the disk to be readable and work again? It has unreplaceable personal items. Any help would be greatly appreciated.

Thanks!
 
Have you tried using the disk in another machine, preferably a machine that has a newer drive? Is the disc a name brand disk that you know was bought from a reputable store?
 
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