I always turn on VSync. I can't stand screen tearing. And wherever possible, I cap my games in-game at 60fps.
I don't play e-sports and I have never actually appreciated "input lags", so it doesn't concern me. Maybe I'm not sensitive to the "input lags".
It's the occassional online server lags that destroys online gaming experience for me. Anyway, I don't like online-only multiplayer games.
I mostly play open world single player games and stealth tactics games when it comes to new games.
I also prefer to play my PC games with wireless Xbox One controller. I still don't appreciate any "input lags".
But the screen tear on the other hand, it totally destroys the feel and flow of the otherwise constant butter-smooth 60fps at highest quality in 1080p or 1440p for me.
Hence, VSync at 60fps is a must for me.