Virus removal in safe mode?

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Hi
My son has a virus on his PC (xp) that has stopped windows from booting up normally, it seems to be on a loop and just returns to the 1st page very time. I cannot get to restore in safe mode
I can open with safe/networking mode. Will scannow sfc solve the problem ?
Can anybody tell me to get windows to boot normally & is it worth running virus/malware etc removal software in safe mode ?.
Thanks for your help
Steve
 
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