Just bought the MAXTOR SATA 300GB HDD w/16MB cache [6B300S0] and my BIOS will not detect it @ all! MOBO: ASUS P4P800 Deluxe I am already running [without any problems] a MAXTOR SATA 120GB hdd [6Y120M0] connected on SATA1 socket. Attempt #1:Tried to plug in the 300GB drive to the SATA2 socket [as a 2nd drive]. Result #1: BIOS does not detect ANY drive, not even the original 120GB drive. Attempt #2: Tried to plug in the 300GB drive on its' own instead of the 120GB drive to SATA1 socket. Result #2: Could not even enter BIOS setup, PC froze after memory count. Furthermore, I even held the drive in my hand with only the power cable hooked up to it, fired up the machine and felt it spinning, so I doubt it's a power issue. Tested the SATA data cable with the original drive and works fine. I also updated the BIOS to the latest version to no avail. MAXTOR told me to try their POWERMAX software on the drive, I don't know how it will detect it but will give it a go. Open to suggestions. Cheers.